Andriol

Decreased sexual activity is a common problem among modern men. If earlier erectile dysfunction was diagnosed mainly in the older generation, today more and more young representatives of the stronger sex turn to the doctor with such complaints. In such cases, andrologists and urologists quite often prescribe Andriol to their patients.

Pharmacological properties

Andriol is an androgenic drug. Its main active ingredient is testosterone undecanoate. It is the main hormone of the male reproductive glands, which is necessary for the normal development and functioning of the male genital organs. In hypogonadism caused by various causes, exogenous testosterone replenishes the endogenous hormone deficiency. Simply put, Andriol is used to increase potency. After internal use, the drug is absorbed in the small intestine. The maximum amount of the active substance is found in blood plasma within 2.5-5 hours after a single use. The high concentration of testosterone is maintained for at least 8 hours. The substance is excreted from the body mainly in the urine and a small amount in the feces. The plasma half-life is 3-4 hours, and the rest of the metabolites leave the body within a week.

Indications for use

• conditions after removal of testes in men
• congenital or acquired eunuchoidism (underdevelopment of the genitals, obesity and skeletal imbalance)
• pituitary insufficiency
• impotence endocrine origin
• male infertility
• menopause in men (premature ejaculation, a noticeable decrease in the amount of sperm during ejaculation, problems with the onset of orgasm, its absence)
• delayed sexual development in boys

All of the above conditions indicate primary or secondary male hypogonadism (androgen hormone deficiency in the body) and require hormone replacement therapy. Andriol can also help men with osteoporosis, which develops against the background of androgen deficiency and with refractory anemia (an intermediate stage between anemia and leukemia). In addition, this drug is used to treat women. It is relevant in complex therapy in the fight against breast cancer, for the treatment of acyclic uterine bleeding in postmenopausal women (the period of life after the cessation of menstruation) and for the elimination of climacteric disorders. Therefore, not only men can be interested in the price of Andriol in a pharmacy.

Contraindications and side effects

And you should also familiarize yourself with the contraindications and possible side reactions of the body. Andriol is contraindicated in such cases:

• patient intolerance to the components of the drug
• diagnosed or suspected oncopathology of the prostate or breast
• kidney damage with severe proteinuria
• during gestation or feeding breastfeeding

Andriol is used with caution in liver failure and other pathologies of the hepatobiliary system, with severe disturbances in the work of the heart, with stable hypertension, frequent migraine attacks or epilepsy. In addition, in the treatment of adolescents who have only approached the age of puberty, systematic observation is recommended so as not to miss the moment of premature closure of the epiphyses of the bones or accelerated puberty. During the treatment process, the following side reactions may develop:

• prolonged, usually painful erections that are not related to sexual arousal
• increased frequency of erections
• decrease in total semen released during ejaculation
• enlargement of the penis
• premature cessation of bone growth in length in adolescents under puberty
• increased blood pressure
• digestive disorders
• muscle weakness
• fluid retention in the body
• skin rashes, itching, acne
• circulatory disorders (increased red blood cell volume in the bloodstream)
• psychoemotional disorders (depression, mood swings, increased or decreased libido)

If the drug is taken by women, then against the background of an excess of male hormones in the body, hair may begin to grow excessively in specific androgen-sensitive areas of the body, where normally their growth is absent or minimal.

Methods of administration and dosage

After the question of how much Andriol costs, patients are interested in how to take this drug. Andriol is available in capsules for oral administration. Each capsule contains 40 mg of testosterone undecanoate. The therapeutic dose should be selected by the andrologist / urologist individually for each patient, taking into account the characteristics of his body and the presence of somatic diseases in the anamnesis.To effectively assimilate synthetic testosterone, the medication should be taken with food. The capsule must be swallowed as it is, it must not be chewed or crushed. The maximum daily dose of Andriol for adults is 160 mg (4 capsules). It is divided into 2 doses (2 capsules) with an interval of 12 hours. On the recommendation of a doctor, replacement therapy in such an amount can last for 14-21 days, and then an effective maintenance dose is selected. Most often, it is 40-120 mg per day (single dose). Although options for a higher or lower dosage are not excluded - it all depends on the positive dynamics in the treatment of pathology and the general well-being of the patient.

Special instructions

In order for it to bring real benefits, it must be properly stored, not taken in excessive quantities and not combined with drugs that can weaken its effect. It is important to take into account the following special instructions: 1. Andriol should be stored at room temperature up to 30C, protected from light and out of reach of children. Do not keep capsules in the refrigerator or even briefly expose them to low temperatures. 2. Despite the fact that Andriol is a low-toxic drug, it should not be abused. If an acute overdose occurs (extremely rarely) with this drug, then symptomatic and supportive therapy is performed. There is no specific antidote. 3. With the joint use of Andriol with drugs that increase the number and activity of metabolic enzymes in the liver (derivatives of barbiturates, Rifampicin, Carbamazepine, Glutethimide), a decrease in serum testosterone concentration may occur, which will affect its activity. 4. If the therapeutic course is protracted, then the patient needs regular monitoring of the liver. As a rule, if the drug was prescribed by a specialist and the patient adheres to all recommendations, then he can count on a favorable prognosis. Although, as a rule, this implies long-term hormone replacement therapy.

Analogs

In the absence of the necessary drug in the pharmacy or for other reasons, patients may be interested in Andriol analogues. They can be divided into 2 groups: 1. The pharmacological group and the active substance are the same. Moreover, such drugs are more correctly called "synonyms". These include - Nebido. This is an injectable drug that contains all the same testosterone undecanoate and has indications for use similar to Andriol. 2. These drugs may differ greatly in composition, but they may have the same diseases / conditions for which they are prescribed. These are the true "analogs". These include Testosterone propionate, Sustanon-250, Androgel, Depo-medrol, Caverject. The patient himself or the pharmacist has the right to select only synonyms for drugs. Selecting analogs is the exclusive prerogative of the doctor, since their composition can negatively affect the patient's condition, taking into account the general indications