Effect of antidepressants on potency

Antidepressants are medications that have a pronounced psychotropic effect on the body. Pharmaceutical drugs used to treat signs of depression affect the levels of neurotransmitters (serotonin and dopamine).

A severe mental health disorder causes a decrease in the background mood, lethargy and lethargy, unfounded fears, emotional stress and anxiety. A person needs a medicine that:

• normalizes his state of health
• eliminates problems with falling asleep
• restores appetite

Indications for the use of antidepressants

Drugs that help patients with mental disorders are used to treat and prevent obsessive-compulsive disorders, enuresis and neuroses, panic conditions and chronic pain syndromes.

Therapy with the use of antidepressants is a common phenomenon when it is necessary to provide medical assistance to a patient suffering from anorexia and bulimia, uncontrolled ejaculation and decreased sexual desire, the consequences of getting rid of alcohol and nicotine addiction. Psychotropic pharmacological agents are often used to treat patients with sleep disorders, hyperexcitability and mood swings.

Mechanism of action of antidepressants

Physicians who are studying the causes and characteristics of the course of depressive disorders have found that the onset of the disease is associated with a lack of monoamines in the synaptic cleft. When it enters the body, a pharmacological preparation performs:

• blocking the breakdown of monoamines (phenylethylamine, serotonin and norepinephrine) as a result of the influence of monoamine oxidases
• suspends the reverse neuronal uptake of monoamines

The systematic use of pharmaceuticals with a sedative effect leads to an increase in the level of neurotransmitters in the synaptic cleft. Drugs with psychotropic properties affect the body of each person in different ways. The severity of the drug effect depends on the antidepressant threshold. The doctor who prescribes antidepressants calculates the level of sedation and stimulation on the patient, taking into account the body's susceptibility to drugs. Taking drugs with antidepressant properties allows you to achieve such results as:

• reduction of stress hyperreactivity of the organs of the pituitary-adrenal system
• reduction of the toxic effect of glutamate
• increase in the activity of monoamines
• elimination of harmful substances contained in the cells of the central nervous system

Effect of antidepressants on male sexual activity

Strong drugs that affect the activity of the nervous system can cause partial or complete loss of sexual desire for the opposite sex. In addition, regular intake of certain psychotropic medications entails a weakening of erection. Tricyclic antidepressants such as amitriptyline and imipramine have intense anticholinergic and antiadrenergic effects. Uncontrolled medication can provoke anorgasmia and suppression of sexual behavior. The negative effect of certain medications with antidepressant effect on male sexual strength is caused by the suppression of the work of nerve endings. The entry into the blood of the components of the drug for depression is the reason for the deterioration of the work of monoaminergic neurons that regulate the activity of the reproductive system.

Contraindications

Doctors do not prescribe drugs with an antidepressant effect to patients if the patient has the following severe organic disorders:

• persistent arterial hypotension or hypertension
• circulatory disorders
• angle-closure glaucoma
• gastric ulcer and duodenal ulcer
• paralytic intestinal obstruction
• thyrotoxicosis
• psychomotor agitation
• convulsive seizures
• acute renal failure
• bladder atony< / li>
• liver disease in the stage of decompensation
• prostatic hypertrophy
• individual drug intolerance

Antidepressants are not recommended for women who are pregnant and lactating. Minors can use psychotropic drugs from the age of 12 after consulting a doctor. A categorical ban on the use of antidepressants applies to patients who have received severe poisoning with alcohol-containing products or psychotropic substances.