Roaccutane 10 mg

Generic Roaccutane is a real breakthrough in the development of skin treatments for acne. It is a drug that can relieve a patient of acne in just one course of treatment. It works according to a simple principle, it acts on the sebaceous glands, forcing them to secrete less sebum. Roaccutane has been awarded the Galen Prize, the equivalent of the Nobel Prize for Pharmaceutical Research. Roaccutane treatment should be started with a dose of 0.5 mg / kg per day. In most patients, the dose ranges from 0.5 to 1 mg / kg of body weight per day. Patients with very severe forms of the disease or with acne in the trunk area may require higher daily doses - up to 2 mg / kg. The recommended course is from 4 to 8 months.

A medicine called Roaccutane is a retinoid used to treat acne. It has anti-inflammatory and anti-seborrheic action.

Composition and form of release

Roaccutane is available in small oval capsules with a volume of 10 or 20 mg. In this article, we will take a closer look at the 10 mg option, represented by brown-red capsules. Each Roaccutane capsule contains a suspension containing:

• Isotretinoin
• Beeswax
• Soybean Oil

The casing consists of a mixture of gelatin, glycerol and various colorants.

Mechanism of action of Roaccutane 10 mg

Regular use of capsules of the drug can improve the clinical picture of acne due to the effect that suppresses the active work of the sebaceous glands by reducing their size. At the same time, the substance isotretinoin has a calming effect, eliminating inflammation. Roaccutane lowers the amount of sebum and restores the normal functioning of skin cells. Reducing the amount of sebum produced, which causes acne, prevents bacteria from growing inside the sebaceous duct.

Indications and contraindications

Roaccutane 10 mg is used to combat severe forms of acne of various types:

• Conglobata
• Nodular-cystic

The drug can help even in cases where other types of therapy are powerless. The drug is strictly prohibited for people suffering from:

• Liver failure
• Hypervitaminosis A
• Hyperlipidemia
• Allergies to Roaccutane ingredients

Also, taking Roaccutane capsules is contraindicated in pregnant women, children under 12 years old and patients taking tetracycline-based medications. Doctors do not recommend the use of Roaccutane for chronic alcoholics, patients with diabetes mellitus, people with obesity or lipid metabolism.

Instructions for taking capsules

Roaccutane should be taken orally simultaneously with food 1-2 times a day. The effectiveness of therapy and the manifestation of side effects are determined by the individual characteristics of the patient's body, therefore the dosage is prescribed by the doctor in strict accordance with the history and severity of the disease. Usually, at the beginning of therapy, the dosage is prescribed at the rate of 0.5 mg per kg of the patient's weight. If the disease is in a severe stage, and acne has spread throughout the body, then the dose can be increased to 2 mg per kilogram of body weight per day. According to research results, the best result is achieved by a course of treatment with a total amount of the drug equal to 150 mg / kg. Accordingly, the period of taking the drug is determined by the individual daily dose. Often, complete remission of acne begins after the 20th week of therapy. If, when taking the prescribed dose, the patient experiences side effects, the prescription is changed in the direction of decreasing it and, as a consequence, extending the course. The vast majority of patients get rid of acne manifestations at the end of one course of taking Roaccutane. In case of relapse, the second course of treatment is carried out with the same dosage. Usually the break between courses is at least two months.

Side effects

Depending on the patient's state of health, while using Roaccutane 10 mg, he may experience the following side effects:

• Periodic increase in ICP in the form of migraines, minor visual impairments and nausea
• Tendency to depressive mood
• Convulsions
• Keratitis
< li>Problems with the organs of vision (changes in light and color perception, conjunctivitis, irritation of the eyelid mucosa, swelling of the optic nerve)
• Nausea or vomiting
• Disorders of the gastrointestinal tract (diarrhea, intestinal inflammation)< / li>
• Rash and itching
• Excessive sweating
• Thinning or hair loss
• Changes in skin condition (dryness, photoallergy, erythema, paronychia, dermatitis)
• Problems wearing contact lenses

Useful information

While taking this medicine, you should not donate blood for donor purposes, since side effects may appear in the recipient.A month before the start of treatment, it is worth monitoring liver function and repeating it every three months. If the norm of the level of liver enzymes is overestimated, the dosage of the drug is reduced. In addition to liver studies, the determination of serum lipids is also carried out. A special diet helps to keep it normal. With diabetes mellitus, it is necessary to increase the glucose level check procedure in order to exclude its increase due to taking the drug. If an exacerbation of acne occurs 2-3 days after taking the drug, you should not change the dose - the manifestations will pass in a week without additional measures. Patients who constantly use contact lenses are advised to wear glasses during the course of treatment with Roaccutane. Women who can become pregnant should start taking reliable contraceptives a month before starting acne therapy with Roaccutane, since its use is strictly prohibited for pregnant women - in case of conception, the pregnancy will have to be terminated. The course of contraceptives should be continued for another month after the end of Roaccutane therapy. Doctors do not recommend sunbathing on the beach or visiting a solarium during treatment. In addition, in the process of taking the drug, it is necessary to observe increased caution in potentially dangerous activities that require quick reaction and extreme concentration (driving a car, extreme sports, working at a machine, etc.). The drug should not be taken simultaneously with tetracycline antibiotics, other retinoids and tetracyclines.