Unidox solution for prostatitis scheme

Unidox Solutab for prostatitis: why and how to use this drug

Unidox Solutab is a pharmaceutical product manufactured in the Netherlands. It comes in the form of tablets, ten units in a blister. Unidox Solutab can also be prescribed by a travel doctor to prevent malaria and traveler's diarrhea.

Unidox Solutab for prostatitis of a bacterial nature is usually used in combination with anesthetic suppositories and other medicines at the discretion of the attending physician.

Used to treat infections caused by pathogens susceptible to the active ingredient, including:

• Pneumonia, chronic bronchitis, and other infections of the chest or lower respiratory tract.
• Bacterial prostatitis at acute and chronic stages.
• Infection of the sinuses (sinusitis).
• Bacterial urinary tract infections and non-gonococcal urethritis.
• Sexually transmitted infections such as gonorrhea, chlamydia, syphilis, lymphogranuloma venereum, and granuloma groin.
• Pelvic inflammatory disease
• Eye infections.
• Infestations caused by microorganisms transmitted by lice, fleas, ticks (e.g. tick fever).
• Infectious diseases of birds that can be transmitted to humans (ornithosis).
• Rare infections caused by Brucella bacteria (brucellosis) that result from contact with infected animals or consumption of contaminated milk or meat.
• Malaria caused by malarial plasmodium resistance.
• Acne vulgaris and rosacea.
• Recurrent mouth ulcers.

Composition

The main active ingredient of the drug is doxycycline at a dosage of 100 mg.

Pharmacological action

Doxycycline belongs to a group of medicines known as tetracycline antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu and other viral infections.

Pharmacodynamics and pharmacokinetics

The mechanism of action of doxycycline contained in Unidox Solutab in prostatitis and other diseases is based on preventing the ability of bacteria to produce the protein they need. Without this protein, bacteria cannot grow and increase in number. Thus, doxycycline stops the spread of infection, and the immune system copes with pathogens already in the body.

Doxycycline is a broad spectrum antibiotic that is active against a wide range of bacteria. However, some strains of bacteria have developed resistance to this drug, which has reduced its effectiveness in treating certain types of diseases. To make sure that the organisms causing the infection are susceptible to doxycycline, your doctor may take a swab from the infected area, or a urine or blood sample.

The maximum amount of the drug in the blood plasma is observed already two hours after oral administration. Excretion from the body of the formed active metabolites and doxycycline unchanged is carried out during urination, inactive metabolites are excreted with feces.

Due to the high concentration of doxycycline in the tissues of the prostate, Unidox Solutab has a pronounced therapeutic effect on prostatitis. It has been established that doxycycline is able to penetrate the hematoplacental barrier, and is excreted in small amounts in breast milk. Because of this, it is not prescribed during lactation and women during pregnancy. Due to the ability of doxycycline to accumulate in the dentin and stain completely unformed teeth yellow, Unidox Solutab is not prescribed for children under 8 years old.

The principle of action and effectiveness in prostatitis

Acute bacterial prostatitis can be considered as a subtype of urinary tract infection.

Two main etiologies of this disease have been proposed:

The most common bacterial prostatitis is caused by Escherichia coli, less commonly by Klebsiella, Proteus, Enterococcus, Staphylococcus aureus, fecal streptococcus, chlamydia, or anaerobes. Because acute prostate infection is often associated with infection elsewhere in the urinary tract, patients may present with symptoms similar to cystitis or pyelonephritis, as well as lower back, perineal or ejaculatory pain, dysuria, frequent urination, and myalgia.

Unidox Solutab for prostatitis has an antibacterial effect on most pathogens of bacterial prostatitis.

This medicine is often prescribed by a doctor as patients respond well to it and side effects are rare.Based on a series of laboratory studies on the penetration of antibiotics in animal models, it was found that the use of tetracycline, trimethoprim-sulfamethoxazole or quinolones has a good effect in bacterial prostatitis.

Method of application and dosage

The standard regimen for taking Unidox Solutab for prostatitis is 100 mg twice a day, lasting two weeks. Each dose of doxycycline should be taken with plenty of water, either in a sitting or standing position. So the medicine will not strongly irritate the throat. Do not take a dose of medication just before bedtime. Doxycycline can be taken with or without food, but if the medicine irritates the stomach, it is best to take it with food or milk.

The duration of therapy has not been well studied. If the patient responds positively to therapy and the causative agent is susceptible to treatment, then most doctors recommend continuing antibiotic treatment for three to four weeks to prevent recurrence, although a longer course is sometimes necessary. About 40% of urologists prescribe an antibiotic for two weeks so that bacteria do not develop resistance to it. Some patients with advanced prostatitis may require hospitalization to receive parenteral antibiotics, usually broad-spectrum cephalosporins and aminoglycosides.

Supportive measures such as antipyretics, analgesics, and stool thinners may also be needed during treatment.

Complete analogues of Unidox Solutab for prostatitis are:

• Doxycycline in capsules manufactured by Borisov Plant of Medicinal Products.
• Doxycycline in capsules manufactured by Alvils Ltd.
• Doxibene in capsules.
• Doxycycline Stada tablets.
• Bassado in capsules.
• Vibramycin capsules
• Doxylan tablets.

Reviews about Unidox Solutab are mostly positive. Patients note that it is better to take the drug after meals and combine it with Linex or similar drugs so as not to harm the intestinal microflora. When taking Unicox Solutab, acne disappeared in many patients. Of the unpleasant side effects, flatulence, indigestion and nausea were noted.

This is a prescription drug.

Unidox Solutab for prostatitis: effective or not

Prostatitis ranks first in terms of frequency of occurrence among male diseases. Already after the age of 30, almost 35% of the stronger sex suffers from it. The causes of its occurrence are often genitourinary infections (chlamydia, mycoplasmas, gardnerella, staphylococci and other bacteria). However, there is also non-bacterial prostatitis.

Both types are divided into acute and chronic forms. But in any case, this rather dangerous ailment with many unpleasant symptoms (weakness, fever, disturbed and painful urination, sexual disorders, irritability, and so on), spoiling the quality of life for men, is treated comprehensively.

That is, phytopreparations and other anti-inflammatory drugs alone are indispensable for prostatitis. For a complete cure in any form, you will need to prescribe antibiotics. Otherwise, if this disease is not treated, it can lead to serious consequences, up to complete infertility or oncology.

But there are quite a lot of varieties of antibiotics now. Which one has proven itself in the best way in getting rid of this ailment? Numerous reviews of those people who have already undergone treatment contain information that Unidox Solutab for prostatitis turned out to be the most effective.

Description of Unidox Solutab and its therapeutic effect depending on the forms of prostatitis

This drug is produced in the form of tablets by the manufacturer Astellas Pharma Europe B.V. It belongs to the tetracycline group of synthetic antibiotics. Its main active ingredient is doxycycline monohydrate. In addition to it, the composition contains substances that enhance the effect of the drug.

It has a wide spectrum of action, therefore, it can have a detrimental effect on many varieties of bacteria, completely blocking specific enzymes inside their cells that provide them with vital processes.

Unidox Solutab from prostatitis, unlike other types of antibiotics, after administration penetrates well into the prostate and accumulates in it (the concentration of the drug in this place can reach 60%). All this makes it advantageous in the choice of agents for therapy against prostatitis, especially in the bacterial form. A considerable number of reviews of most urologists confirm this.

If the cause was not an infection, Unidox Solutab with prostatitis of this form is still most often prescribed. It relieves inflammation well, which in this ailment will in any case be present. It also has a preventive effect, preventing the growth of pathogenic microflora against the background of this process.After all, it can aggravate the course of the disease.

Using Unidox Solutab for prostatitis

This drug is well absorbed in the intestines, and its effectiveness does not depend on food intake. The maximum concentration of the main component in the prostate after use occurs in about 2-3 hours.

The traditional treatment regimen with Unidox Solutab includes taking tablets every 12 hours at a daily dosage of 200 mg for 2 to 4 weeks.

However, doctors do not always adhere to this appointment, since usually the course is selected personally and depends on many factors:

As you can see, the list of nuances for the competent preparation of an individual treatment regimen is considerable. And often, for this, the urologist must focus on a number of laboratory tests. Therefore, this drug should be used strictly for its intended purpose, under its careful control. Moreover, Unidox Solutab has many more contraindications and side effects.

Side effects and contraindications

Unidox Solutab from prostatitis has a depressing effect not only on harmful bacteria, but also on beneficial ones too. Therefore, after taking it, dyspeptic symptoms may begin against the background of developed dysbacteriosis. It can also contribute to the activation of the growth of Candida fungi, which, in turn, can cause candidiasis of the mucous membranes of the mouth or rectum.

This drug can cause severe allergies if there is such a reaction of the body to tetracycline derivatives. It is able to reduce the number of platelets in the blood, which can serve to reduce hemoglobin. This, in turn, may lead to hypovitaminosis.

In the process of taking Unidox Solutab for prostatitis, such uncomfortable conditions may be felt as:

• nausea;
• lack of appetite;
• bloating;
• headaches.

As for contraindications, their list is as follows:

• risk of developing allergies;
• severe impairment of kidney and liver function;
• diseases of the hematopoietic system;
• porphyria.

Analogues of the drug and approximate prices

But, like other medicines, it also has analogues. Some of them are more expensive, while others are cheaper.

On the basis of monohydrate, there are not so many variants that completely coincide in chemical composition with the drug described here. This compound is formed during a long and complex purification process using expensive high-tech equipment.

There are also domestic analogues made on the basis of another type of doxycycline - hyclate. These include Doxilan, Vidoccin, Dovicin, Tetracycline, Doxycycline

Such a price run is not in vain. After all, the pharmacological effectiveness of, for example, Doxycycline is approximately only 50%, while the same indicator for expensive analogues based on monohydrate is up to 95%.

Composition and action of the medicine

Each tablet contains 100 mg of doxycycline monohydrate and a number of excipients. This ensures the stability of the dosage form.

The drug belongs to the tetracycline series of antibiotics, acts bacteriostatically. Violates the synthesis of protein structures in the microbial cell. In this case, the microbe itself does not die, but its reproduction is suppressed. As a result, the number of pathogens decreases sharply until they disappear completely.

A feature of the dosage form "solutab" is the presence of the active substance in microspheres. This protects the medication from being destroyed by stomach acid and enzymes. As a result, the drug is released only in the duodenum. This ensures rapid absorption and entry of the drug into the bloodstream, minimal irritating effect on the gastric mucosa. Also, its suppressive effect on the microflora of the digestive tract is significantly reduced.

In an acute process, as a rule, monotherapy is used. In the presence of several pathogens resistant to antibacterial agents, which is more often detected in chronic prostatitis, 2 or more antibacterial drugs are indicated. If Unidox Solutab is used simultaneously with bactericidal antibiotics that disrupt the formation of the cell membrane and cause the death of microbes (penicillins, cephalosporins, fluoroquinolones), their therapeutic effect is sharply reduced. It is acceptable and effective to use it together with other bacteriostatics (macrolides, nitrofurans).

How and how many days to take

In urological practice, treatment of prostatitis with Unidox is prescribed for:

• acute inflammation of the prostate and exacerbation of chronic bacterial prostatitis;
• sexually transmitted infections - with lesions of the genitourinary system as a result of infection with gonorrhea, chlamydia, ureaplasmosis;
• complex treatment of prostate adenoma.

Contraindicated for men with:

• previously identified intolerance or hypersensitivity to any member of the tetracycline group;
• diagnosed severe disorders of the liver (including porphyria) and kidneys.

According to the instructions, Unidox Solutab should be taken at a daily dosage of 200 mg on the first day, with a further transition to 100 mg every 24 hours. The duration of treatment for prostatitis depends on its clinical efficacy and tolerability. The course of treatment of an acute process is from 5 to 10 days, and in most cases - 1 week. Chronic inflammation, especially when microflora resistant to most antibiotics is detected, is an indication for an increase in the duration of therapy: up to a maximum of 3-4 weeks (under the control of indicators of the liver, kidneys and the dynamics of the inflammatory process).