Tamoxifen for impotence

Tamoxifen is an antiestrogen with antitumor effects. The basis of the drug is tamoxifen citrate. Doctors classify this pharmacological agent as a subgroup of sex hormones.

Tamoxifen is unique and potent and must be taken under medical supervision. The use of tablets without prescription can cause serious complications in the condition of a man with impotence. The pharmaceutical preparation is prescribed mainly for women, athletes and cancer patients. Regular intake of the drug substance can significantly increase the level of testosterone in the blood. after 10 days of using the medication, the level of the sex hormone of the age is 40%. As a result of taking tamoxifen citrate for a month and a half, testosterone levels increase by 80%. Tamoxifen differs from other medications in its rather slow action. To achieve noticeable results, the patient needs to undergo a long course of treatment. Among the advantages of a pharmacological substance, experts note its high safety and ability to reduce the risk of developing cardiac pathologies.

Indications for use

The drug is prescribed to the following categories of persons:

• women and men after the development of estrogen-dependent cancers of the skin, breast and kidney, anterior pituitary gland, and melanoma or soft tissue sarcoma
• women affected by ovarian or endometrial cancer
• men who have tumors in the prostate area

Tamoxifen is usually recommended by a doctor if the patient's body is resistant to other drugs. The positive effect of the drug on men with sexual dysfunctions is to cure cancer diseases that affect the organs of the reproductive and endocrine systems, to normalize the plasma testosterone concentration.

Pharmacological action of the drug

An anticancer drug contains metabolites that compete with estradiol for the junction with cytoplasmic estrogen receptors in the tissues of internal organs. Unlike estrogen, the tamoxifen receptor complex does not increase DNA production in the nucleus, but slows down cell division. The described results entail regression and subsequent death of tumor cells.

Peculiarities of drug metabolism

After resorption of dragees with tamoxifen citrate, the active components enter the bloodstream after 4 hours. To achieve the maximum effect after a single use of the medication, it takes about 7 hours. It is possible to achieve a sufficient increase in the concentration of the drug in the blood serum 3-4 weeks after the start of drug therapy. Subsequently, the anticancer drug is metabolized in the liver and excreted from the body along with urine. Complete elimination of traces of Tamoxifen in plasma occurs approximately one week after the application of the medication.

Dosage

An antiestrogenic pharmacological agent is taken in strict accordance with the instructions of the attending physician. Typically, medical professionals choose a daily dosage for patients in the range of 20-40 mg. The pill should be drunk 2 times a day - in the morning and in the evening. The pharmaceutical substance must be swallowed whole with a little clean water. For long-term use, a dose of 20 mg is ideal. If, after prolonged use of the drug, the doctor detects further growth of a malignant neoplasm, then the drug is canceled.

Side effects of the medication

Taking an increased dosage of medication can provoke side effects such as:

• an allergic reaction, such as redness and itching of the skin
• headache, dizziness
• decreased mood background and depressive symptoms
• drowsiness, increased fatigue and confusion
• visual disturbances such as changes in the cornea and decreased visual acuity, cataracts and retinopathy
• thrombophlebitis and thrombocytopenia, thromboembolism and transient leukopenia
• hypercalcemia
• severe liver dysfunction, increased liver enzymes
• epigastric pain, nausea and vomiting, constipation and lack of appetite
• itching in the genital area, difficulty urinating
• fever and hot flashes

Contraindications

The drug is not prescribed for women during pregnancy and breastfeeding. Men cannot take medication for individual intolerance, and also: