Papaverine for erectile dysfunction

Papaverine is a highly effective drug for the treatment of a wide range of functional pathologies. The medicine is used for intracavernous injections. The entry of this pharmacological product into the blood allows achieving a double hemodynamic effect, namely:

• dilate the penile arteries and narrowed veins;
• trigger the veno-occlusive mechanism.

Most preparations based on papaverine hydrochloride can be found in the form of solutions intended for injection. Bitter in taste, the product dissolves easily in chloroform.

Indications for use

A medicinal substance helps to cope with painful conditions that were provoked by spasmolytic contractions of smooth muscles in the area:

• peripheral vessels (endarteritis)
• cerebral vessels
• abdominal organs (pylorospasm and colitis, cholecystitis and renal colic)
• heart ( severe angina)
• respiratory organs

Symptoms of erectile pathology

Doctors recommend taking papaverine for erectile dysfunction to those groups of patients who suffer from severe vascular disorders. If we consider this disease from the point of view of harmful consequences for the reproductive system, then the following pathological signs can be distinguished:

• decreased erectile ability. It is expressed in defective sexual arousal and may be characterized by insufficient blood filling of the penis, incomplete swelling of the cavities, partial increase in the length, volume and level of firmness of the penis. This condition does not allow a representative of the stronger sex to make full sexual contact and causes severe psychogenic disorders;
• loss of erection. An adult patient may suffer from organic pathologies leading to impaired formation and maintenance of a spontaneous and adequate erection. In this state, patients have a complete absence of sexual abilities, leading to infertility and a decrease in the emotional background;
• a short duration of sexual intercourse. In patients with vascular pathologies, there is a violation of the mechanisms of maintaining an erection. As a result, patients experience decreased sexual stamina. The erection disappears within the first minute after penetration into the vagina. There is a possibility of relaxation of the penis without prior ejection of sperm, which indicates damage to the centers of ejaculation;
• psychogenic impotence. Numerous problems that arise in the stronger sex in the process of intimacy lead to psychogenic depression. Pathological conditions can cause reactive and neurotic factors, long-term sexual failure, which lead to disappointment from the sexual partner, family problems and divorce.

Complications

The disease is often complicated by alcohol, drug or nicotine addiction. A man may come to the conclusion that psychotropic substances and potent antidepressants will help him cope with anxiety and difficult moral experiences. As a result of unauthorized intake of potent pharmaceuticals, the patient can cause deterioration in the work of other spheres and internal organs. Thus, the doctor will have to lengthen the treatment period and use stronger medications. Clinical manifestations of vascular disorders can occur as a result of an increase in atherosclerotic changes that reduce arterial flow to the corpora cavernosa. With an increase in blood clots, clinical symptoms of angina pectoris and disturbances in the blood supply to the brain occur

Pharmacological action

Papaverine provides antispasmodic and hypotensive effects. It is a non-selective phosphodiesterase inhibitor. To achieve the maximum tonic effect, the drug can be used in combination with phentolamine and alprostadil. When papaverine hydrochloride enters the human body, it relaxes the smooth muscles of the internal organs. The general muscle tone of the organs of the respiratory and cardiovascular, digestive and respiratory, excretory and reproductive systems decreases.

Method of administration and dosage

Papaverine for erectile dysfunction is prescribed in a dosage of 40-60 mg three times a day.With the introduction of increased doses of isotonic sodium chloride solution, patients may experience the following symptoms:

• blurred vision in the form of double vision
• lowering blood pressure
• general weakness, constant drowsiness

Contraindications

Papaverine is not recommended for the correction of erectile dysfunction in men suffering from:

• hypersensitivity
• AV block
• severe liver failure
• glaucoma

This sexual strength and stamina tonic is not intended for use in minors or the elderly.

Restrictions on use

Reception of a potency stimulator must be performed under medical supervision if the patient has a history of shock and craniocerebral trauma, supraventricular tachycardia, adrenal dysfunction and renal failure, shock and prostatic hyperplasia.