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Phosphodiesterase type 5 inhibitors: drugs for men


Phosphodiesterase Type 5 Inhibitors Drugs For Men

Sexual impotence affects more and more men - especially for residents of megacities. Type 5 phosphodiesterase inhibitors help to cope with the problem. The drugs presented on the domestic market are in great demand.



What are type 5 phosphodiesterase inhibitors?


Sexual life is an important aspect of the relationship between a man and a woman. erectile dysfunction is becoming a problem, and more recently, even at a relatively young age. Type 5 selective phosphodiesterase inhibitors come to the rescue. These are drugs that block the production of the corresponding enzyme.


The choice of drugs in this group is quite wide, but the general effect that phosphodiesterase inhibitors have is to increase erection and increase its duration. But only if there is sexual arousal. Simply put - the effect of the drugs will be only when the partner makes you want. These are not pathogens. Therapy with such drugs solves the problem at the root, but only acts symptomatically.



Mechanism of Action


Every man chooses for himself ways to increase potency and return male strength. Phosphodiesterase inhibitors are considered to be one of the most effective today; their mechanism of action is aimed at blocking the type 5 phosphodiesterase enzyme. Thanks to this effect, the amount of another enzyme increases, which helps to relax the smooth muscles of the arteries of the penis.


The cavernous bodies of the penis fill with blood and an erection occurs.


After ejaculation, everything returns to the "starting point". Depending on the drug chosen, the exposure time may vary. But when it ends, the symptom returns.


Therefore, for the next sexual exploits it is necessary to take a new dose. As an "ambulance" or "rapid response agent", such drugs are perfectly acceptable. But to eliminate the cause of the phenomenon, you need to use complex therapy aimed at treating the underlying ailment.



The best drugs for men


Since we are talking about the representatives of the stronger sex, who do not like doctors in principle, and even more so those who treat sexual dysfunctions, then drugs to improve the potency of a single use suit them perfectly. So, we present to your attention the best phosphodiesterase inhibitors. Classification by active ingredient.



Viagra


The working substance of Viagra is sildenafil.


Indications for use:



  • erectile dysfunction (complete or partial);
  • weakening of erection, which leads to the impossibility of full sexual intercourse;
  • premature ejaculation that occurs before contact or in the first minutes.

Viagra should be taken in a carefully selected dosage, which can only be done by a specialist.


You need to drink one tablet or dissolve one dragee under the tongue (if it is a Soft series) 25-30 minutes before the expected sexual activity. The effect lasts for 4 to 6 hours, depending on the initial indication, individual characteristics and the dose of the drug.


There are a lot of contraindications:



  • serious pathologies of the cardiovascular system, causing persistent heart rhythm disturbances;
  • eye pathologies in which irreversible processes occur in the retina;
  • renal and hepatic pathologies;
  • during exacerbation of ulcerative and erosive diseases of the gastrointestinal tract;
  • deformity of the penis caused by fibrotic tissue changes.

The daily dose should not exceed 100 mg, and for older men - 50 mg.


Among the side effects, the loss of color perception is especially often noted (it is restored after the medication stops working).



Maxigra


A synthetic inhibitor of phosphodiesterase 5 type of Polish production, more affordable, has high efficiency, can be taken from 20 years to old age, as indicated in the instructions for use.


Contraindications are similar to the previous remedy, since the main component is sildenafil. However, due to the additional components, its aggressive action is less pronounced. In any case, caution should be exercised (consultation with a doctor is required).


A pill is taken an hour before the "romantic date" (best on an empty stomach), the effect lasts for 12 hours. As a result of the reception, the quality of intercourse improves, a stronger erection and full ejaculation are observed.


The medicine has no effect on fertility, therefore, when planning a pregnancy, there are no special indications about taking it. It is not recommended to combine with alcohol (especially for hypertensive patients with heart problems).



Sialil


The active substance of Cialis is tadalafil. Helps a man to strengthen an erection and increase the quality and duration of intercourse.


Action time - up to 36 hours. This is the longest period of erection maintenance for this type of product.


You need to take the medicine 15 minutes before sex. The recommended dose starts at 10 to 20 mg. Additionally, the product is available in the Soft series, in the form of fruit-flavored dragees, which must be absorbed under the tongue. The peculiarity of these sweet pills is that they act faster than traditional ones, which must be taken into account.


Exceeding the dosage is not recommended in order to avoid the manifestation of undesirable consequences in the form of:



  • increased heart rate;
  • increase in blood pressure;
  • nausea and vomiting;
  • Stool disorders.

Contraindications are standard, but it is noted that men after suffering strokes and heart attacks are allowed to take the minimum dose, but not earlier than six months after treatment.



Levitra


The main component is vardenafil. It is used in the treatment of erectile dysfunction, to increase potency, improve the quality and duration of intercourse, enhance the sensations during orgasm.


Available in dosages of 5, 10, 20 and 40 mg of active ingredient per tablet. There is a series of Soft - dragees for sucking under the tongue. They have a pleasant fruity taste and act faster than the usual tablet form. In addition, they can be combined with a small amount of alcohol and fatty foods, which is contraindicated when using the standard form.


Reception classic - 15-30 minutes before sexual activity. The effect lasts for 4-6 hours, depending on the dose and characteristics of the organism, as well as the degree of sexual dysfunction.


Contraindications:



  • individual intolerance to the components of the drug;
  • simultaneous reception with antihypertensive drugs of strong action;
  • low blood pressure;
  • under 20 years old.

People with impaired kidney and liver function, as well as men over 65 years old should limit themselves to a dosage of 5 mg (no more than once a day).



Zidena


Udenafil is a synthetic type 5 phosphodiesterase inhibitor. The drug is indicated for the treatment of sexual dysfunctions in men of different ages.


Effective dosage - 1 tablet (100 mg) 30-60 minutes before intercourse. Erectile function is maintained for 4-6 hours, depending on the initial symptoms.


Contraindications:



  • adolescence (under 18);
  • hypersensitivity to the composition of the drug;
  • concomitant use with medications containing nitrates or nitrogen donors.

With great care and after consulting a doctor, it can be used by men in such situations:



  • hypotension or uncontrolled hypertension;
  • eye diseases with degenerative phenomena in the retina;
  • after bypass surgery, stroke or heart attack (earlier than six months);
  • severe liver or kidney failure;
  • blood diseases, especially with an increased prothrombin index (excessive clotting);
  • cardiovascular pathologies in which increased physical activity is contraindicated.