Potency increasing substances

In pharmacology, a group of substances is distinguished that can regulate the state of male potency. These drugs can be used to increase libido and restore erectile function.

Functions of drugs for impotence

The drugs developed for men with reduced potency are designed to return patients to the ability to experience strong libido and activate the cells of the parasympathetic nervous system, which are responsible for transmitting the signal about the development of an erection. Medicines have a complex effect and have a stimulating effect at all stages of erection development, including at the stage:

• accumulation of cyclic guanosine monophosphate (cGMP) in the cavernous tissue of the penis
• reducing the tone of the smooth muscle walls of the arteries that carry blood along the groin
• compression of the venous ducts and blocking the outflow of blood from the organs small pelvis

Modern pharmacological agents eliminate the problems associated with insufficient potency and erectile dysfunction, which have arisen due to:

• delayed release of erection mediator
• cGMP deficiency
• decrease in the level of sensitivity of vascular tissue
• insufficient compression of veins due to an increase in connective tissue

Classification of stimulant drugs

Medicines needed to get rid of various problems in the sexual sphere can be divided into the following groups:

• drugs that increase the secretion of nitric oxide (selective PDE5 inhibitors in the form of tadalafil, sildenafil or vardenafil, as well as NO synthase activators that have a homeopathic effect)
• alpha-blockers (selective and non-selective type )
• prostaglandin E analogs
• hormonal substances that stimulate increased testosterone production
• myotropic antispasmodics

Phosphodiesterase Inhibitors

These pharmaceuticals are classified as first-line drugs for the treatment of intimate problems. Medicines have a peripheral effect, including:

• enhance the effect of the transmitter
• promote active blood flow to the groin

Medicines give a temporary effect that lasts from 4 to 36 hours, depending on the nature and amount of the active substance taken. The onset of the tonic effect can be observed 30-60 minutes after taking the pill.

NO-synthase activators

Homeopathic remedies such as Impaza contain purified human antibodies that are involved in the secretion of nitric oxide. Impaza restores the work of blood vessels, increases the level of sexual arousal. The drug can increase the production of nitric oxide by endothelial cells. The advantage of the drug is that its active components do not affect the work of the cardiovascular system, do not entail changes in blood pressure indicators.

Alpha blockers

Yohimbine and phentolamine slow down the postsynaptic alpha-adrenergic receptors. As a result, the mechanism of transmission of adrenergic vasoconstrictor impulses is disrupted. This entails blocking the detumescence process and increasing the time of intercourse.

Prostaglandin E analogs

Alprostadil has a relaxing effect on the smooth muscles of the corpora cavernosa, improves blood microcirculation in the intimate area and causes the development of a stable erection. The drugs of this group do not affect the process of ejaculation and do not eliminate male infertility. The active components of the drug substance bind to receptors on the cell surface and change the level of adenylate cyclase activity, accelerate the release of cAMP, and relax the smooth muscle fibers of the cavernous arteries. The drugs can cause intense hypotensive and vasodilatory effects, sometimes lead to the development of priapism or prolonged erection, which negatively affects the state of the cavernous tissues.

Testosterone

The biologically active androgen is used to help individuals who need replacement therapy. A natural hormonal substance shown to a man suffering from hypogonadism.

Myotropic antispasmodics

Papaverine causes enlargement of the penile arteries and narrowing of the venous walls. The drug allows you to increase the flow of arterial blood to the penis and achieve a persistent erection.