Will ofloxacin help with prostatitis

Composition and principle of action when sorry

Ofloxacin is available in tablets and solutions for injection with a dosage of 200 mg. The main active ingredient is ofloxacin, the auxiliary components include:

It has a selective pharmacological action. Upon contact with infectious agents, the drug penetrates into the nucleus of the latter and binds the enzymes that are responsible for DNA replication (DNA gyrase). The action is called bacteriostatic (stops the reproduction of microorganisms).

In the case of prostatitis, it is these antibiotics that should be used. If you use bactericidal drugs (which destroy microorganisms), then a large amount of endotoxins will enter the blood and prostate tissues. They provoke a strong withdrawal, against the background of which acute urinary retention may occur.

If you take the drug in tablet form, after absorption in the intestine, it enters the liver. In it, Ofloxacin is metabolized with the help of cytochromes and phosphatase. Metabolites of the drug have the same high bacteriostatic activity as the drug itself. Part of the drug binds to bile and enters the intestines and kidneys, which are excreted unchanged. The other part binds to proteins and penetrates the prostate.

When used in the form of injections, the drug immediately enters the organs and stops the reproduction of microorganisms. In acute prostatitis or exacerbation of chronic it is better to take the medicine in injectable forms. Ofloxacin tablets can be used to treat prolonged bacterial or chronic inflammation of the prostate gland.

The maximum concentration in the blood plasma occurs after 2-3 hours. The drug penetrates well through hematological barriers and accumulates in physiological fluids. There are times when taking antibiotics for an inflamed prostate is ineffective. This is due to the fact that they do not penetrate into the liquid environment of the gland, where bacteria multiply. Ofloxacin accumulates not only in the tissues of the organs themselves, but also enters the secretion of the prostate, blocking all the ways for the survival of microorganisms.

The drug is removed after 12-24 hours. The speed depends on the functional state of the kidneys and liver.

Ofloxacin is a very powerful broad-spectrum antibiotic. It can be prescribed even without determining the true causative agent of prostatitis. With a 14-day course, 75% of all possible pathogens of inflammation die.

How to use it

The dosage and treatment regimen of Ofloxacin depends on such indicators as:

• cause;
• duration of illness;
• complications due to the disease;
• functional state of the kidneys and liver;
• taking other antibacterial drugs.

Ofloxacin can be taken in the range of 100 to 800 mg. The frequency of use depends on the prescribed dose. If prescribed up to 400 mg - take once a day, if more than 400 mg - 2 times a day. The dose should be divided into two equal parts.

The average therapeutic course of Ofloxacin for prostatitis takes a week. There are exceptions. If the disease is chronic and the infection is resistant to antibiotic therapy, the course of treatment is extended to 14 or even 28 days. In acute forms caused by translocation (movement) of E. coli from the intestine to the prostate gland, the course of treatment is from 7 to 10 days. In the gonorrheal form, 400 or 600 mg of Ofloxacin are used once.

If there is kidney disease against the background of the underlying disease, the dose is gradually reduced

When treating for more than 14 days, it is recommended to use probiotics and hepatoprotectors. If other antibiotics are used along with Ofloxacin, the course of treatment may be reduced to 5 days.

The dose for acute prostatitis is 400-600 mg. For the treatment of chronic, 400 mg tablets are more often used, but with longer courses. With purulent complications, the dosage increases to 800 mg.

Contraindications and side effects

The main contraindication is hypersensitivity to any of the components of the drug. The drug should not be prescribed to people with decompensated chronic diseases, in particular the kidneys and liver.

Ofloxacin is not given to people with impaired heart function in the form of blockades, myocardial hypertrophy and rheumatic lesions of the valvular apparatus. Relative warnings are tachycardia and extrasystole.

The drug is strictly contraindicated in people with epilepsy and the risk of seizures. You can not take it with anticonvulsants and antiarrhythmic drugs.

Side effects occur infrequently. With a long course, more than 10 days, secondary infections may occur in the form of a fungal infection of the skin and mucous membranes. Due to the fact that the antibiotic acts mainly on the gram-negative flora, intestinal dysbacteriosis often occurs.

On the part of the respiratory system, there have been cases of dry cough, which disappears after discontinuation of the drug. There are allergic reactions in the form of redness and rash, dermatitis.

Ofloxacin should be used with caution long-term in people who have diabetes mellitus. In rare cases, taking the medication is accompanied by hyper- and hypoglycemia (changes in blood glucose levels).

The most common Side effects are headache and dysfunction of the lacrimal glands. Liver dysfunction and cholestasis occur. When the drug is discontinued, the symptoms disappear.

Levofloxacin or Ofloxacin: which is better

Both drugs are representatives of a group of broad-spectrum antibiotics - fluoroquinolones. The antimicrobial effect extends mainly to gram-negative microorganisms.

Both drugs have analogues, they are used to treat prostatitis. The difference between antibiotics is that Levofloxacin belongs to a new generation of drugs and its antimicrobial effect is more pronounced. When taking Levofloxacin, side effects are less common, and the active substance is better excreted from the body. The difference lies in the price: Levofloxacin is more expensive.

Drugs can be replaced if allergic reactions occur to one of them, or if Ofloxacin is ineffective. In practice, such substitutions are rare. It also makes no sense to take both drugs at the same time, since they have the same mechanism of action and do not potentiate the effect of each other.

Six months ago, the doctor prescribed a course of Ofloxacin for 10 days. I took it 1 time per day. There were no side effects. Pain in the perineum, caused by inflammation of the prostate gland, has passed, the condition has improved. I also took the drug for cystitis, the effect was positive.

He got bacterial prostatitis after unprotected sex. Microbes were found in the culture from the prostate. I was prescribed a course of antibiotics, which included Levofloxacin. Took 7 days, cured, had diarrhea a couple of times, but possibly not related to the antibiotic.

For more than 3 years he had been ill with chronic prostatitis, he was worried about constant pulling pain and urination disorders. I also often suffer from pyelonephritis. At the next exacerbation, I decided to try Ofloxacin, the condition improved, but only slightly. Then I replaced the drug with another, from the same series - Levofloxacin, the effect was better.

Ofloxacin for prostatitis: effectiveness and application

Ofloxacin is an antimicrobial drug that affects a large number of pathogenic microorganisms that can cause infectious diseases. When it enters the body, it blocks the production of an enzyme in a bacterial cell that affects its vital activity. In this case, the structure of many components of the bacterium is disrupted, which leads to irreversible death.

Types of microorganisms sensitive to Ofloxacin:

• Gram-negative.
• Gram-positive.
• Tuberculosis mycobacteria.
• Mycoplasmas.
• Chlamydia.
• Gardnerella.
• Ureaplasma.
• Trichomonas

Issue Form

The drug is produced in the form of round tablets of white color, covered with a thin film, which dissolves under the action of enzymes of the digestive system. Tablets are sold in packs of 10, packed in cardboard boxes, with a dosage of 200 or 400 mg.

There is also an infusion solution (100 ml vials) and eye ointment (tubes of 3 and 5 g).

The active substance in all dosage forms: ofloxacin.

Shell composition: titanium dioxide, macrogol 4000, hypromellose, propylene glycol, talc.

The action of the drug in prostatitis

Due to its ability to be completely absorbed when used, Ofloxacin penetrates well into the tissues of the prostate gland, where its concentration after application is 100%. Due to such a high level of concentration of this drug in the prostate, it has an active effect here on the microorganisms that caused prostatitis. All this helps to quickly get rid of this unpleasant disease.

Indications and contraindications

Indications for use:

• Pneumonia.
• Bronchitis.
• Cholecystitis
• Pyelonephritis
• Laryngitis
• Sinusitis
• Furuncles
• Chlamydia.
• Urethritis
• Prostatitis
• Gonorrhea.
• Cystitis
• Colpitis
• Endometritis
• Neutropenia

• Hypersensitivity to the components that make up the medication.
• Impaired cerebral circulation.
• Tendon lesions.
• Deficiency of glucose - 6 - phosphate dehydrogenase.
• Chronic renal failure.
• Epilepsy.
• Cerebral atherosclerosis.
• Lowered seizure threshold.
• Organic lesions of the central nervous system.
• Pregnancy and lactation
• Childhood and adolescence.

Instructions for use and dosages for prostatitis

This drug is used only in the treatment of chronic inflammation of the prostate gland. In this case, tablets are used, a dosage of 400 mg. It is recommended to use the drug 2 times a day, one tablet. Ofloxacin is recommended to be used one hour before or 2 hours after a meal. Tablets must be swallowed whole, washed down with plenty of boiled water.

Most often, the therapeutic course lasts about 20 days. According to individual indications, it can be extended as prescribed by the attending physician.

Side effects

• Nausea.
• Stool disorders.
• The urge to vomit.
• General weakness.
• A feeling of bitterness in the mouth.
• Meteorism.
• Pain in the abdomen.
• Headache.
• Hallucinations.
• Convulsions.
• Nightmares.
• Depressive states.
• Confusion.
• Violation of taste sensations.
• Reducing blood pressure.
• Rapid heartbeat
• Skin rash and itching.
• Thrombophlebitis.

The active substance in all analogues of this drug is ofloxacin.

• Ofloxin: available in tablet form. It has a pronounced antimicrobial effect.
• Zanocin: release form - tablets, film-coated. Has an antibacterial effect.
• Oflohexal: also available as a bactericidal tablet.
• Oflobac: tablet form for the treatment of acute and chronic inflammation of the prostate gland. Affects pathogenic microorganisms, causing their death.

How to take Ofloxacin for prostatitis?

Prostatitis is a fairly common disease among men. This pathology cannot be cured without the qualified help of a specialist. Therapy needed to eliminate inflammation of the prostate involves taking antibiotics. Many antibacterial drugs have been developed that help to cope with the inflammatory process, as well as get rid of pain. The most common use is "Ofloxacin" for prostatitis.

Description and composition

For prostatitis, broad-spectrum antibiotics are widely used. They have a detrimental effect on all types of microbes and bacteria, and speed up the healing process.

Ofloxacin is an antimicrobial drug that belongs to the fluoroquinolone group

Description of "Ofloxacin":

The composition of the drug includes the active ingredient of the same name. The auxiliary components are:

• corn starch;
• pavidon;
• calcium stearate;
• lecithin;
• additives E171, E132 and E122.

Issue Form

Medication for sale in the form:

Often for prostatitis, "Ofloxacin" is prescribed in the form of tablets. If therapy is carried out in a hospital, the drug can be administered as an injection. This method of treatment is more effective. The active substance is absorbed into the bloodstream and begins to exert a pharmacological effect. The patient can take the pills at home only after the doctor approves the dosage and course of treatment.

It has been used for 15 years, so Ofloxacin is considered effective in bacterial prostatitis

Pharmacological action

"Ofloxacin" with prostatitis has a detrimental effect on most harmful microorganisms. Once in the body, the active substances contribute to the destruction of DNA chains, which leads to the inevitable death of bacteria and microbes. The active substance is effective not only against gram-positive, but also detrimental to gram-negative bacteria. Among them are:

• salmonella;
• ureoplasma;
• chlamydia;
• mycoplasma;
• listeria;
• streptococci;
• staphylococci;
• Clostridia and others.

After taking the tablets, the active substance is quickly absorbed into the walls of the gastrointestinal tract and after two hours the drug begins to act. Parallel food intake slows down absorption and reduces the effectiveness of the active substance. The drug does not adversely affect the work of other body systems. The medicine is excreted naturally along with urine.

When is it necessary to prescribe "Ofloxacin"?

Since the drug is detrimental to pathogenic microbes, it is prescribed in various fields of medicine. Often in the list of recommended drugs "Ofloxacin" is in the treatment of:

ENT diseases - respiratory tract infections of varying severity: bronchitis, pneumonia, sinusitis, pharyngitis.Due to the enhanced action and elimination of various types of bacteria, the drug is effective for prostatitis

• Genital infections in men and women.
• Bacterial diseases of the skin, abdominal cavity, joints, pelvic organs.

An antibiotic is also prescribed after open band surgeries to prevent re-infection. Purulent diseases of the skin, ears, and other parts of the skin can not do without the intervention of bacteria, so antibiotic therapy will also be effective and necessary. "Ofloxacin" is useful both at the initial stage and in the chronic course.

Contraindications and side effects

Like all drugs, a drug from the genus of fluoroquinolones has a number of contraindications. At risk are:

Pregnant and lactating women. No type of antibiotics is indicated for this group of patients. Broad-spectrum antibiotics have a negative impact on the course of pregnancy and the fetus. Children under 18. Individuals with traumatic brain injury. Patients after a stroke. People with an allergy or intolerance to one of the substances in the drug. Therefore, it is advisable to first find out if a person has such a contraindication. Like any antibiotic, Ofloxacin has its own contraindications and side effects

Ofloxacin often does not cause any side effects in patients. However, in pharmacology, the following symptoms are distinguished that can be observed during the treatment of inflammation of the prostate:

• loss of appetite;
• dizziness;
• nausea;
• vomit;
• loose stools;
• depressive state;
• depression;
• headaches;
• hearing impairment;
• smell reduction;
• Incorrect color perception.
• disorders on the part of the locomotor system.

The presence of side effects should alert the patient. It is unacceptable to prescribe an antibiotic without the knowledge of a doctor. Treatment is carried out only under the supervision of an experienced specialist.

The use of "Ofloxacin" for inflammation of the prostate

Often, doctors prescribe a drug in the form of tablets to eliminate prostatitis.

Treatment scheme:

Special Considerations

Prostatitis is a pathology caused by a certain type of microorganism. In absolutely all cases, careful studies are carried out before antibiotic therapy. This is necessary to identify the type of pathogen. Prostate juice is examined, and swabs are taken from the urethra. With the help of laboratory tests, the reaction of bacteria to a particular drug is determined.

The treatment regimen with Ofloxacin is selected by the urologist

At the end of therapy, control tests are taken. At the appointment, the doctor, using ultrasound and palpation, evaluates the result of the treatment, and also draws conclusions about the effectiveness of the drug in the inflammatory process.

Be careful when taking medication, if available:

• allergy;
• renal or liver failure. Reception of funds is carried out under the close supervision of a doctor. Specialists must constantly monitor the condition of the kidneys and liver in order to prevent violations;
• epilepsy.

Interaction of "Ofloxacin" with other drugs

If you are taking other drugs along with the antibiotic, be sure to tell your doctor about it. Ofloxacin, as well as many drugs used at the same time, require certain rules to be followed:

People with psychomotor disturbances are advised not to drive while taking antimicrobials.

Drug Benefits

Many doctors speak positively in favor of Ofloxacin. Its rapid action helps to eliminate the unpleasant symptoms observed during exacerbation of the inflammatory process of the prostate. There is no need to take other medicines. Antimicrobial activity is detrimental to most bacteria. The effect becomes noticeable already for 3-4 days. Urination improves, the patient can return to normal life. The main advantage of this medicine is its active action in chronic forms of the disease and the prevention of complications. Tablets are also effective in the field of ophthalmology and otolaryngology.

Originally posted on 2017-07-12 10:04:06.